Quantitative and objective evaluation of disease severity and/or drug effect is necessary in clinical practice.Wearable accelerometers\nsuch as an actigraph enable long-term recording of a patient�s movement during activities and they can be used for quantitative\nassessment of symptoms due to various diseases. We reviewed some applications of actigraphy with analytical methods that are\nsufficiently sensitive and reliable to determine the severity of diseases and disorders such as motor and nonmotor disorders like\nParkinson�s disease, sleep disorders, depression, behavioral and psychological symptoms of dementia (BPSD) for vascular dementia\n(VD), seasonal affective disorder (SAD), and stroke, as well as the effects of drugs used to treat them. We believe it is possible to\ndevelop analytical methods to assess more neurological or psychopathic disorders using actigraphy records.
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